Version: 1.0.0 | Published: 8 Oct 2024 | Updated: 229 days ago
Documentation
Associated Media:
Description:
The Moorfields Dry-AMD Dataset encompasses all patients with advanced dry AMD, specifically geographic atrophy (GA), and without choroidal neovascularization, at Moorfields Eye Hospital - a leading provider of eye health services in the UK and a world-class centre of excellence for ophthalmic research and education. A detailed description of the dataset definitions can be found below.
Inclusion criteria:
- a posterior free hand draw label of ‘Geographic’ or (ii) at least one reference in their clinical notes to ‘geographic atrophy’
Exclusion criteria:
- Patients under the age of 50 at their most-recent imaging event
- Patients with at least one reference in their clinical notes to ‘Stargardt’
- Patients with a record of injections of any type
- Patients with a posterior free hand draw label of ‘Choroidal neovascularization’
The dataset will include any imaging or clinical metadata that is available for these patients. In the instance where only one eye meets the criteria above, both eyes are included in the dataset. For these reasons, the dataset will include longitudinal data from where a patient underwent monitoring during the early and intermediate stages of the disease.
Clinical metadata includes information regarding:
- patient demographics
- visual acuities (predominantly measured with Early Treatment Diabetic Retinopathy Study (ETDRS) charts)
- ocular surgeries
Additional information is provided in the ‘technical details’ tab.
The Dry-AMD dataset includes eye imaging modalities, such as:
- Optical coherence tomography (CSO, Heidelberg, Optos, Topcon, Zeiss)
- Colour fundus photographs (Topcon, Zeiss)
- Ultra-wide field photographs (Optos, Zeiss)
- Iris photographs (CSO, Zeiss)
- Keratoscope topography (CSO)
- Infrared photographs (Heidelberg, Topcon, Zeiss)
- Fluorescein angiography (Heidelberg, Optos, Topcon, Zeiss)
- Indocyanine green angiography (Heidelberg, Optos, Topcon)
- Fundus autofluorescence (Heidelberg, Optos, Zeiss)
Imaging data from CSO is subject to additional approvals.
As of July 2024, the dataset consisted of 11,168 eyes and over 688,018 ophthalmic images.
Coverage
Typical Age Range:
38-103
Follow Up:
> 10 Years
Pathway:
The dataset is representative of the entire pathway for patients receiving
treatment for age-related macular degeneration (AMD) at Moorfields Eye Hospital
NHS Foundation Trust .
Provenance
Origin
Purposes:
Study
Collection Situations:
- Clinic
- Secondary care - Accident and Emergency
- Secondary care - Outpatients
- Secondary care - In-patients
Temporal
Accrual Periodicity:
Continuous
Start Date:
01 March 2001
Time Lag:
1-2 weeks
Accessibility
Access
Access Rights:
Access Service:
INSIGHT has established a Secure Research Environment (SRE) to provide
researchers with a computing environment that meets the security levels required
by regulation, with the power needed for analysis of large datasets. In addition
to the SRE, INSIGHT may provide approved researchers with alternative data
access methods, such as data egress, subject to meeting security conditions. For
more information please visit our SRE website
https://www.insight.hdrhub.org/secure-research-environment.
Access Request Cost:
Delivery Lead Time:
Not applicable
Jurisdictions:
GB-GBN
Data Controller:
Moorfields Eye Hospital NHS Foundation Trust
Usage
Data Use Limitations:
General research use
Data Use Requirements:
Project-specific restrictions
Format and Standards
Vocabulary Encoding Schemes:
- SNOMED CT
- DM+D
- NHS NATIONAL CODES
Languages:
en
Formats:
- CSV
- Image
Observations
Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Persons
11,168 Eyes with 688,018 Images
7305
Patients
30 June 2024