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Version: 1.0.0 | Published: 8 Oct 2024 | Updated: 228 days ago

Observational Cohort Trial OCTAVE (OCTV)

Dataset

Documentation

Description:
OCTAVE is a multi-disease, observational, cohort trial that will seek to understand the immune response to SARS-CoV-2 vaccinations in patients with certain immunosuppressed conditions. Cohorts will include patients with chronic renal conditions, chronic liver conditions, inflammatory bowel disease, cancer (both solid and haematological malignancies), immune-mediated rheumatic/inflammatory conditions and haematopoietic stem cell transplant (HSCT) and chimeric antigen receptor (CAR) T recipients. OCTAVE is a collaborative research project involving academic partners from the Universities of Glasgow, Birmingham, Oxford, Imperial College London and the IMPACT network. The project is funded by the Medical Research Council, and badged as an Urgent Public Health trial supported by the NIHR Clinical Research Network.

Coverage

Spatial:
United Kingdom
Typical Age Range:
0-120
Follow Up:
Other
Pathway:
Covid-19, Cohorts will include patients with chronic renal conditions, chronic liver conditions, inflammatory bowel disease, cancer (both solid and haematological malignancies), immune-mediated rheumatic/inflammatory conditions and haematopoietic stem cell transplant (HSCT) and chimeric antigen receptor (CAR) T recipients.

Provenance

Origin

Sources:
Other
Collection Situations:
  • Other
  • Secondary care - In-patients

Temporal

Accrual Periodicity:
Daily
Start Date:
01 January 2023
Time Lag:
Less than 1 week

Accessibility

Access

Access Service:
The SAIL Databank is powered by the UK Secure e-Research Platform (UKSeRP). Following approval through safeguard processes, access to project-specific data within the secure environment is permitted using two-factor authentication.
Access Request Cost:
Data provision is free from SAIL. Overall project costing depends on the number of people that require access to the SAIL Gateway, the activities that SAIL needs to complete (e.g. loading non-standard datasets), data refreshes, analytical work required, disclosure control process, and special case technological requirements.
Delivery Lead Time:
Not applicable
Jurisdictions:
GB-GBN
Data Controller:
SAIL Databank
Data Processor:
SAIL Databank

Usage

Data Use Limitations:
Research-specific restrictions
Data Use Requirements:
  • Project-specific restrictions
  • User-specific restriction
Resource Creators:
Digital Health and Care Wales (DHCW)

Format and Standards

Vocabulary Encoding Schemes:
LOCAL
Languages:
en
Formats:
SQL database table

Observations

Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Persons
Patients with immunocompromised or immunosuppressed conditions.
5000
Count
29 September 2021