Documentation
Description:
New! The three year follow-up observations are now incorporated into the GERAS Study - US to now offer researchers baseline, 18 month, and 3 year follow-up data.
The GERAS Study - US was a prospective, multicenter, observational study that aimed to assess societal costs and resource use associated with AD among patients and their primary caregivers across 76 sites in the United States. Eligible patients were between the ages of 55 and 85 years at baseline, met criteria for early AD in the opinion of the enrolling physician, had Mini-Mental State Examination (MMSE) scores ≥20 and had study partners who were willing to participate. Participants were classified as mildly cognitively impaired ([MCI]; MMSE score 24-30 and Functional Activities Questionnaire [FAQ] <6) or MILD (mild dementia; MMSE 20-30 and FAQ ≥6). Subsequent stages further classified participants as either amyloid positive or negative. Data collected for patients and caregivers included demographics/clinical characteristics; current medication; patient cognitive, functional and behavioral assessments; patient and caregiver health-related quality of life (HRQoL); and patient and caregiver resource use. The costs associated with the resources used were calculated. Costs were broken down into patient healthcare costs, patient social care costs and caregiver informal care costs. A total of 1,198 patients were evaluated (300 MCI amyloid positive, 281 MCI amyloid negative, 317 MILD amyloid positive, 300 MILD amyloid negative). Overall, patients had a mean age of 70.4 years with a slight preponderance of females (55.3%).
The companion GERAS - Japan study is available here: https://discover.alzheimersdata.org/catalogue/datasets/c06f96e4-2fa1-4c5d-850c-90dda0e760a1.
The companion GERAS II study is available here: https://discover.alzheimersdata.org/catalogue/datasets/07a5233b-b2f4-4709-b132-e69e96eef9ed.
The companion GERAS - EU study is available here: https://discover.alzheimersdata.org/catalogue/datasets/c4fdff84-b1f4-4d1a-bf6c-4798916532b2.
Please find the baseline manuscript here: https://content.iospress.com/download/journal-of-alzheimers-disease/jad190430?id=journal-of-alzheimers-disease%2Fjad190430.
To explore the data further, visit GAAIN: https://www.gaaindata.org/partner/GERAS-US
Coverage
Spatial:
US
Follow Up:
Unknown
Provenance
Temporal
Accrual Periodicity:
Static
Start Date:
01 January 2026
Time Lag:
Not applicable
Accessibility
Access
Access Rights:
See dataset for details. Access data at:
Usage
Resource Creators:
Observations
Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Persons
1198
Count
01 January 2026