Documentation
Description:
The GERAS II study was a prospective, multicenter, observational study that aimed to assess societal costs and resource use associated with AD among patients and their primary caregivers in Italy and Spain. Eligible patients were males and females aged ≥55 years old, who had received a diagnosis of probable AD according to the National Institute on Aging and Alzheimer’s Association and with a Mini-Mental State Examination (MMSE) score of 26 or less. At baseline, patients were stratified into groups based on AD severity as measured through their MMSE score (mild: MMSE 21-26, moderate: MMSE 15-20, and moderately severe/severe [MS/S]: MMSE < 15). Data collected for patients and caregivers included demographics/clinical characteristics; current medication; patient cognitive, functional and behavioural assessments; patient and caregiver health-related quality of life (HRQoL); and patient and caregiver resource use. The costs associated with the resources used were calculated. Costs were broken down into patient healthcare costs, patient social care costs and caregiver informal care costs. In Italy, 198 patients (29 mild; 80 moderate; 89 MS/S) were enrolled with mean age at baseline 77.5 years, 60% female. In Spain, a total of 380 participants (116 mild; 118 moderate; 146 MS/S) were enrolled with mean age 75.7 years, 63% female.
The companion GERAS - EU study is available here: https://fair.addi.ad-datainitiative.org/#/data/datasets/the-geras-study-EU.
The companion GERAS - Japan study is available here: https://fair.addi.ad-datainitiative.org/#/data/datasets/the_geras_study___japan.
The companion GERAS - US study is available here: https://fair.addi.ad-datainitiative.org/#/data/datasets/the_geras_study___us.
Please find the baseline manuscript outlining findings from Italy here: https://link.springer.com/article/10.14283%2Fjpad.2017.31?utm_medium=affiliate&utm_source=commission_junction&utm_campaign=3_nsn6445_brand_PID100357191&utm_content=de_textlink
and the baseline manuscript outlining findings from Spain here: https://www.cambridge.org/core/journals/international-psychogeriatrics/article/abs/costs-and-quality-of-life-in-communitydwelling-patients-with-alzheimers-disease-in-spain-results-from-the-geras-ii-observational-study/90921EE600D3DA33DD77790D83813DE2.
Coverage
Spatial:
US
Follow Up:
Unknown
Provenance
Temporal
Accrual Periodicity:
Static
Start Date:
01 January 2026
Time Lag:
Not applicable
Accessibility
Access
Access Rights:
See dataset for details. Access data at:
Usage
Resource Creators:
Observations
Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Persons
578
Count
01 January 2026