Version: 1.0.0 | Published: 23 Sep 2026 | Updated: 0 days ago
Documentation
Description:
Description of population: The 10/66 dementia research program is a population-based study comprising in principle all older residents aged 65 years and over, living in 11 geographically defined urban and rural catchment area sites in eight low- and middle-income countries. The 10/66 research program was developed to address dementia prevalence, incidence, and impact across Latin American countries, China, and India, using a validated and standard methodology. Given that the program implemented by the Dementia Research Group 1066 (DRG10/66) has become a population-based cohort study, the scope of the research is now much broader and entail a comprehensive inquiry into health (common and burdensome chronic diseases, disability and health service utilization) and social aspects of aging (socioeconomic status, social protection, needs for care and care arrangements). The 10/66 DRG protocols also included a full neurological disease assessment and a physical and neurological exam. All interviewers and field examiners received uniform and standardized training.
Data being contributed to AD Data Initiative is from the 6 Latin American countries/territories in the 10/66 population-based cohort. Urban sites were selected to comprise mixed or mainly lower socioeconomic status households; exclusively high-income or professional districts were excluded. Urban sites were located in Cuba (one catchment area comprising sites is Havana and Matanzas), Dominican Republic (Santo Domingo), Puerto Rico (Bayamon), Venezuela (Caracas), Peru (Lima), Mexico (Mexico City). Rural sites, selected to be remote from major population centers, with low-density population and with agriculture and related trades as the main local employment, were located in Peru (Canete Province), Mexico (Morelos State).
The cohort at baseline, with respect to vital status ascertained through to March 2014, comprised 15,901 elderly participants. The follow-up period ranged from 2.8 to 5.0 years by site, with a total of 53,872 person-years of follow-up. With respect to the incidence of dementia in the 6 Latin American countries/territories, 14,896 participants were interviewed at baseline, 13,483 free of dementia; 9322 (69.1%) were re-interviewed, contributing 42,698 person-years of follow-up. Sociodemographic and health characteristics of participants by country are provided in Table 1.
Type of data: Demographics, lifestyle risk factors, non-communicable disease, clinical and cognitive interview, physical exams, MCI and dementia diagnosis. Participant and Informant questionnaires (including measures of caregiver burden).
Link to cohort paper:
https://academic.oup.com/ije/article/46/2/406/2617175
Link to 10/66 protocols paper:
https://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-7-165
Relevant papers:
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(08)61002-8/fulltext
https://www.thelancet.com/article/S0140-6736(12)60399-7/fulltext
Coverage
Spatial:
US
Follow Up:
Unknown
Provenance
Temporal
Accrual Periodicity:
Static
Start Date:
01 January 2026
Time Lag:
Not applicable
Accessibility
Access
Access Rights:
See dataset for details. Access data at:
Usage
Resource Creators:
Jorge Llibre-Guerra
Observations
Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Persons
14896
Count
01 January 2026