Version: 1.0.0 | Published: 27 Aug 2026 | Updated: 14 days ago
Documentation
Associated Media:
Description:
An observational study in young adults (aged 18-39) with cancer, diagnosed with lymphoma, melanoma or testicular cancer. Fear of cancer recurrence (FCR) is a recognised psychological consequence of a cancer diagnosis and can affect quality of life.
This study integrated a FCR assessment (the FCR-4 four item questionnaire ) within a follow-up clinic, and depending on the score, participants were recommended one of three different approaches:
*10 or lower (low risk) received standard care (no specific focus on FCR).
*10-16 (moderate risk) were offered the MiniAFTERc cognitive behavioural therapy intervention (delivered by Clinical Cancer Nurse Specialists over the telephone) to help with the negative consequences of FCR.
*over 16 were assessed for possible referral to psychological services.
As well as FCR4, questionnaires were used to assess Quality of life, anxiety, depression, and fatigue - at baseline, 1 month and 3 months, in all cohorts.
In addition participants in the Mini-AFTERc arm, and the CCNSs were asked their experience using Mini-AFTERc, and it"s acceptability.
Coverage
Spatial:
Sutton LB, United Kingdom
Typical Age Range:
18-39
Follow Up:
0 - 6 Months
Pathway:
Participants were identified from young people (aged 18-39) diagnosed with
lymphoma, melanoma or testicular cancer at the Royal Marsden. Participants were
asked to complete a FCR-4 questionnaire (4 questions associated with fears of
cancer returning) to screen them for risk associated with FCR. Those scoring 10
or lower (low risk) were recommended to standard care (no focus on FCR). Those
scoring 10-16 (moderate risk) were offered the MiniAFTERc (cognitive behavioural
therapy) intervention, delivered by Clinical Cancer Nurse Specialists CCNSs over
the telephone. Those scoring over 16 (higher risk) were assessed for possible
referral to psychological services. FCR4, Quality of life, anxiety and
depression, fatigue questionnaires were completed by all participants at
baseline, 1 month and 3 months. Participants in the Mini-AFTERc arm, along with
the CCNSs, were additionally asked about the acceptability of the intervention.
In addition some participants and CCNSs were interviewed about their experience
of being part of this study. Participants in the Mini-AFTERc arm were
additionally asked about the acceptability and their experience around the
intervention as will the nurses that delivered it.
Provenance
Origin
Purposes:
Study
Sources:
Other
Collection Situations:
Cohort, study, trial
Temporal
Accrual Periodicity:
Static
Start Date:
01 April 2025
End Date:
16 January 2026
Time Lag:
Not applicable
Accessibility
Access
Access Rights:
in progress
Access Service:
Although not required, there is an option to use The Royal Marsden’s Trusted
Research Environment and informatics platform: BRIDgE (Biomedical Research
Informatics Digital Environment). BRIDgE is managed by The Royal Marsden’s
Information Team with support by the NIHR Biomedical Research Centre at The
Royal Marsden and ICR. The aim of the platform is to transform clinical practice
and improve outcomes for patients by enabling researchers to access real-world
cancer data within secure, collaborative, cloud-based workspaces. Learn more by
visiting the BRIDgE site within the NIHR BRC area of The Royal Marsden and ICR
website: https://www.cancerbrc.org/BRIDgE
Access Request Cost:
Depends on type of access. Costing available on application.
Delivery Lead Time:
Variable
Jurisdictions:
UK
Data Controller:
Royal Marsden NHS Foundation Trust
Data Processor:
Royal Marsden NHS Foundation Trust
Usage
Data Use Limitations:
Research-specific restrictions
Data Use Requirements:
- Institution-specific restrictions
- Ethics approval required
- Not for profit use
- User-specific restriction
Resource Creators:
The Royal Marsden NHS Foundation Trust; The Royal Marsden Cancer Charity; NIHR Biomedical Research Centre at The Royal Marsden and the ICR
Format and Standards
Vocabulary Encoding Schemes:
LOCAL
Conforms To:
LOCAL
Languages:
en
Observations
Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Persons
Participants from single hospital. "Observation date" is date of study closure, actual recruitment was over six month period
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16 January 2026