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Version: 1.0.0 | Published: 8 Jan 2026 | Updated: 51 days ago

TNT - A phase III RCT of carboplatin vs docetaxel for patients with metastatic or recurrent locally

Dataset

Documentation

Description:
TNT is a phase 3, parallel group, open-label randomized controlled trial. 376 participants were allocated (in a 1:1 ratio) to groups that received six cycles of carboplatin (AUC 6), day 1 of a 3-weekly cycle, or six cycles of docetaxel (100 mg/m2), day 1 of a 3-weekly cycle. Subjects were offered six cycles of the alternative (crossover) treatment upon progression or where allocated treatment was discontinued due to toxicity (pre-progression crossover). Clinical data and sample collection.

Coverage

Spatial:
United Kingdom

Provenance

Temporal

Accrual Periodicity:
Static
Start Date:
30 April 2018
Time Lag:
Not applicable

Accessibility

Access

Access Rights:
Please contact the publisher using Contact Point details provided
Access Request Cost:
Not specified
Delivery Lead Time:
Other
Jurisdictions:
UK
Data Controller:
The Institute of Cancer Research
Data Processor:
The Institute of Cancer Research

Format and Standards

Vocabulary Encoding Schemes:
LOCAL
Conforms To:
LOCAL
Languages:
en
Formats:
In Progress