Version: 0.0.5 | Published: 24 Jul 2023 | Updated: 668 days ago
Documentation
Associated Media:
Description:
ALSPAC was established to understand how genetic, biological, environmental, social, psychological and psychosocial factors influence the health and development of children and their parents. ALSPAC is a multi-generation prospective cohort based in Bristol in the South West of England. More than 14,000 women (G0) were enrolled in 1991 and 1992. Their partners (also G0), children (G1) and now grandchildren (G2) have been recruited and followed up over multiple timepoints. A wide variety of biological samples have been collected along with a vast array of exposure and outcome data collected via questionnaire, face to face clinics and through linkage to administrative data.
During the index pregnancy women were sent 3 questionnaires. Since then, over a period of some 25 years, women have been sent almost annual questionnaires asking about their own health and well-being. From 2008, women were invited to attend four focus clinical assessments. Assessments of the children have been administered frequently, with multiple data collection time points since birth. These include numerous child-completed questionnaires, a number of clinical assessments from the age of 7 years and further questionnaires about the child completed by the mother or other main caregiver. Partners of the mothers have also completed a number of questionnaires and been invited to one focus clinic assessment. The second generation (children of the children) have been and continue to be recruited with data collected via questionnaire and clinical assessment at multiple time points.
The study has multiple datasets arranged by cohort member, data type (usually questionnaire or clinic) and time point. In addition, the study reacted quickly to the COVID-19 pandemic and has multiple data collections available from March 2020.
Is Part Of:
Birth Cohort study
Coverage
Spatial:
United Kingdom
Typical Age Range:
0-150
Follow Up:
> 10 YEARS
Physical Sample Availability:
- DNA
- FAECES
- PLASMA
- SALIVA
- SERUM
- URINE
Provenance
Origin
Purposes:
STUDY
Sources:
- ELECTRONIC SURVEY
- PAPER BASED
Collection Situations:
- CLINIC
- HOME
Temporal
Accrual Periodicity:
ANNUAL
Distribution Release Date:
01 February 2021
Start Date:
01 April 1991
Time Lag:
6 MONTHS PLUS
Accessibility
Access
Access Rights:
Access Service:
Bespoke datasets are shared directly with the researcher unless administrative
data is required (e.g. health or educational records) in which case UKSerP is
used.
Access Request Cost:
Delivery Lead Time:
1-2 WEEKS
Jurisdictions:
GB
Data Controller:
University of Bristol
Data Processor:
University of Bristol
Usage
Data Use Limitations:
GENERAL RESEARCH USE
Data Use Requirements:
NOT FOR PROFIT USE
Resource Creators:
ALSPAC Study Team
Investigations:
Is Referenced By:
Offspring Cohort Profile: Boyd A., Golding J., Macleod J., Lawlor D.A., Fraser A., Henderson J., Molloy L., Ness A., Ring S., Davey Smith G. Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children. International Journal of Epidemiology 2013; 42(1): 111-127. Mothers Cohort Profile: Fraser A, Macdonald-Wallis C, Tilling K, et al.: Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort. International Journal of Epidemiology 2013; 42(1): 97–110. Cohort Profile Update: Northstone K., Lewcock M., Groom A., Boyd A., Macleod J., Timpson N., Wells N. Cohort Profile:The Avon Longitudinal Study of Parents and Children (ALSPAC): an update on the enrolled sample of index children in 2019
Format and Standards
Conforms To:
LOCAL
Languages:
en
Formats:
any flat file format can be provided (.csv, stata, SPSS, R)
Enrichment and Linkage
Qualified Relations:
Up to date information is available here: http://www.bristol.ac.uk/alspac/researchers/our-data/linkage/
Derivations:
Derived variables are added to relevant datasets as opposed to us having derived datasets per se
Origin
Name:
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