Version: 1.0.0 | Published: 13 Oct 2025 | Updated: 55 days ago
Assess determinants and understand strategies which may delay/halt aortic stenosis progression
Dataset
Documentation
Description:
Aortic Stenosis is a condition which affects a valve in the heart by causing it to become stiff and narrowed, it develops over a number of years and affects mainly only older adults. The narrowing is caused by calcium build up on the valve making it stiff and difficult to open. The rate at which the valve narrows varies between people and is affected by the presence of other conditions and a protein in the blood called lipoprotein a. Currently the only treatment is valve replacement. However, for a score/tool to be developed which can categorise people according to their risk of rapidly progressing from mild to moderate to severe disease. Knowing who the rapid progressing are will allow for risk factor management and using a drug which lowers Lp(a) to slow disease progression avoiding the need for valve replacement.
Coverage
Spatial:
West Midlands
Provenance
Origin
Purposes:
Study
Sources:
EPR
Temporal
Accrual Periodicity:
Static
Distribution Release Date:
02 July 2025
Start Date:
01 January 2007
End Date:
01 January 2020
Time Lag:
Variable
Accessibility
Access
Access Rights:
Information Governance and Ethics - West Midlands Secure Data Environment (https://westmidlandssde.nhs.uk/information-governance-and-ethics)
Access Service:
Data Request Process - West Midlands Secure Data Environment
(https://westmidlandssde.nhs.uk/research/data-request)
Access Request Cost:
Please email wmsde@uhb.nhs.uk
Delivery Lead Time:
Variable
Jurisdictions:
GB
Data Controller:
University Hospitals Birmingham NHS Foundation Trust
Data Processor:
University Hospitals Birmingham NHS Foundation Trust
Usage
Data Use Limitations:
Research-specific restrictions
Data Use Requirements:
- Ethics approval required
- Project-specific restrictions
Resource Creators:
This publication uses data from the PATHWAY, an ethically approved Research Data Hub (NRES Reference 22/EE/0161)
Format and Standards
Vocabulary Encoding Schemes:
- ICD10
- SNOMED CT
- OPCS4
Conforms To:
LOCAL
Languages:
en
Formats:
CSV