Version: 1.0.0 | Published: 13 Oct 2025 | Updated: 55 days ago
Feasibility testing of digital platform to capture PROs for CAR-T precision cellular therapies
Dataset
Documentation
Description:
The field of precision cellular therapy is forecast to undergo rapid expansion in the coming decade and there is an urgent need for evidence-based tools, co-produced with patients, to better support the growing number of individuals with haematologic malignancies who will receive these potentially curative treatments. The novelty of Chimeric Antigen Receptor T-cell (CAR-T) therapies, the unique and potentially severe toxicities associated with these treatments, and emerging evidence of long-term and late-effects of treatment mean effective symptom monitoring is key to maximising treatment benefit and ensuring patient safety. Development of predictive models that include ePRO data have been developed for other cancers and therapies; however, these systems may not be appropriate for monitoring the distinctive symptom profiles associated with CAR-T cellular therapy, providing the warrant for this research.
Coverage
Spatial:
West Midlands
Follow Up:
Other
Provenance
Origin
Purposes:
Study
Sources:
EPR
Temporal
Accrual Periodicity:
Static
Distribution Release Date:
30 September 2025
Start Date:
01 January 2019
End Date:
30 June 2025
Time Lag:
Variable
Accessibility
Access
Access Rights:
Information Governance and Ethics - West Midlands Secure Data Environment (https://westmidlandssde.nhs.uk/information-governance-and-ethics)
Access Service:
Data Request Process - West Midlands Secure Data Environment
(https://westmidlandssde.nhs.uk/research/data-request)
Access Request Cost:
Please email wmsde@uhb.nhs.uk
Delivery Lead Time:
Variable
Jurisdictions:
GB
Data Controller:
University Hospitals Birmingham NHS Foundation Trust
Data Processor:
University Hospitals Birmingham NHS Foundation Trust
Usage
Data Use Limitations:
Research-specific restrictions
Data Use Requirements:
Project-specific restrictions
Resource Creators:
This publication uses data from the PATHWAY, an ethically approved Research Data Hub (NRES Reference 22/EE/0161)
Format and Standards
Vocabulary Encoding Schemes:
- ICD10
- OPCS4
Conforms To:
LOCAL
Languages:
en
Formats:
CSV