Version: 1.0.0 | Published: 9 Apr 2024 | Updated: 410 days ago
Documentation
Associated Media:
Description:
The Moorfields DMO Dataset is a longitudinal dataset consisting of routinely collected imaging and clinical metadata from patients receiving treatment for Diabetic Macular Oedema (DMO) at Moorfields Eye Hospital NHS Foundation Trust, from 2004 to the present.
This dataset encompasses all patients at Moorfields Eye Hospital NHS Foundation Trust - a leading provider of eye health services in the UK and a world-class centre of excellence for ophthalmic research and education - who have received at least one injection of either Lucentis (ranibizumab) or Eylea (aflibercept) for DMO. These therapies began at Moorfields in 2013, however, the dataset will include any imaging or clinical metadata that is available for these patients prior to that time (for example in patients who were initially monitored or received other treatments prior to receiving treatment). Also of note, this dataset will include data from both eyes in each case - for example, it will include data from fellow eyes that are not receiving injections. For these reasons, the dataset will include longitudinal data from a wide range of diabetic eye disease.
Clinical metadata includes demographic information, visual acuities (predominantly measured with Early Treatment Diabetic Retinopathy Study (ETDRS) charts), diabetic retinopathy grading, and information regarding intravitreal therapies and ocular surgeries.
Imaging metadata includes colour fundus photographs, optical coherence tomography (OCT) scans (Topcon, Heidelberg), fundus autofluorescence (Heidelberg), fluorescein and indocyanine green angiography (Heidelberg).
This dataset is continuously updated. As of September 2021, it comprised of over 3,200 eyes receiving Lucentis or Eylea for DMO, over 42,700 injection episodes, and over 806,000 ophthalmic images. This is the largest single centre database from patients with DMO and covers more than a decade of follow-up for these patients.
Is Part Of:
Not Applicable
Coverage
Typical Age Range:
26-89
Follow Up:
> 10 YEARS
Physical Sample Availability:
OTHER
Pathway:
The dataset is representative of the entire pathway for patients receiving
treatment for diabetic macular oedema (DMO) in the Medical Retina service at
Moorfields Eye Hospital NHS Foundation Trust.
Provenance
Origin
Purposes:
STUDY
Sources:
- EPR
- MACHINE GENERATED
- OTHER
Collection Situations:
- ACCIDENT AND EMERGENCY
- CLINIC
- IN-PATIENTS
- OUTPATIENTS
Temporal
Accrual Periodicity:
CONTINUOUS
Time Lag:
1-2 WEEKS
Accessibility
Access
Access Rights:
Access Service:
INSIGHT is developing its data access environment for researchers. INSIGHT
releases anonymised data, under strict data licence arrangements, to external
secure environments, subject to appropriate due diligence and contracting.
Access Request Cost:
Delivery Lead Time:
2-6 MONTHS
Jurisdictions:
GB-ENG
Data Controller:
Moorfields Eye Hospital NHS Foundation Trust
Data Processor:
Not Applicable
Usage
Data Use Limitations:
GENERAL RESEARCH USE
Data Use Requirements:
PROJECT SPECIFIC RESTRICTIONS
Resource Creators:
INSIGHT Health Data Hub
Format and Standards
Vocabulary Encoding Schemes:
- DM+D
- NHS NATIONAL CODES
- SNOMED CT
Conforms To:
- NHS DATA DICTIONARY
- OTHER
Languages:
en
Formats:
- CSV
- Image
Enrichment and Linkage
Qualified Relations:
None
Derivations:
Not Applicable
Observations
Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Persons
3,219 Patients
6,378 Eyes with 806,581 Images
4,516 Eyes with 42,729 Injections (Lucentis/Eylea)
6,438 Eyes with 204,724Visual Acuity Readings
3219
COUNT
30 September 2021