Version: 1.0.0 | Published: 10 Apr 2024 | Updated: 408 days ago
Documentation
Associated Media:
Description:
The impact of hospitalised patients with COPD: from admission to outcome
Dataset 13.0
Background. Chronic obstructive pulmonary disease (COPD) is a debilitating lung condition characterised by progressive lung function limitation. COPD is an umbrella term and encompasses a spectrum of pathophysiologies including chronic bronchitis, small airways disease and emphysema. COPD caused an estimated 3 million deaths worldwide in 2016, and is estimated to be the third leading cause of death worldwide. People with COPD experience flares in their symptoms, termed exacerbations. Exacerbations are associated with increased mortality, morbidity, a faster decline in lung function and other systemic illness such as heart attacks and strokes. Despite this impact, COPD exacerbations are poorly characterised and have been without novel treatments for >30 years.
PIONEER geography The West Midlands (WM) has a population of 5.9 million & includes a diverse ethnic & socio-economic mix. There is a higher than average percentage of minority ethnic groups. The West Midlands has a high prevalence of COPD, reflecting the high rates of smoking and industrial exposure. Each day >100,000 people are treated in hospital, see their GP or are cared for by the NHS.
EHR. University Hospitals Birmingham NHS Foundation Trust (UHB) is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & 100 ITU beds. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”.
Scope: All hospitalised patients admitted to UHB with an exacerbation of COPD from Jan 2000 - 2021. Longitudinal & individually linked, so that the preceding & subsequent health journey can be mapped & healthcare utilisation prior to & after admission understood. The dataset includes ICD-10 & SNOMED-CT codes pertaining to COPD and COPD exacerbations, as well as all co-morbid conditions. Serial, structured data pertaining to process of care (timings, staff grades, specialty review, wards), presenting complaint, all physiology readings (pulse, blood pressure, respiratory rate, oxygen saturations), all blood results, microbiology, all prescribed & administered treatments (NIV, nebulisers, antibiotics), all outcomes. Linked images available (radiographs, CT).
Available supplementary data: Ambulance, 111, 999 data, synthetic data. Non-COPD “controls”
Available supplementary support: Analytics, Model build, validation & refinement; A.I.; Data partner support for ETL (extract, transform & load) process, Clinical expertise, Patient & end-user accs, Purchaser access, Regulatory requirements, Data-driven trials, “fast screen” services.
Is Part Of:
NOT APPLICABLE
Coverage
Spatial:
United Kingdom, England, West Midlands
Typical Age Range:
15-110
Follow Up:
OTHER
Physical Sample Availability:
NOT AVAILABLE
Pathway:
The West Midlands (WM) has a population of 5.9million & includes a diverse
ethnic, socio-economic mix. There is a higher than average percentage of
minority ethnic groups with Birmingham having a population which is >40%
non-white. WM has a large number of elderly residents. There is social
deprivation and Birmingham’s population suffers with particularly high rates of
COPD; as well as high rates of physical inactivity, obesity, smoking,
hypertension, ischaemic heart disease & diabetes. There are also high levels of
rare diseases, especially immunometabolic conditions. The patients included in
this dataset are representative of this diverse population and also include a
wide age-range. University Hospitals Birmingham NHS Foundation Trust (UHB) is
one of the largest NHS Trusts in England, providing direct acute services &
specialist care across four hospital sites, with 2.2 million patient episodes
per year, 2750 beds & 100 ITU beds. UHB runs a fully electronic healthcare
record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care
record (Your Care Connected) & a patient portal “My Health”. This dataset
includes the patient journey from admission to hospital to outcome for patients
with known COPD or where a diagnosis of COPD was made or suspected on admission.
The data includes granular demography and co-morbidity, presenting symptoms and
diagnoses, serial physiology and blood biomarkers, all investigations, all
prescribed and administered treatments and outcomes. It can be supplemented with
preceding and following health care contacts, to understand the risk for the
acute admission and the subsequent impact on health after discharge. Although
primarily secondary care, this dataset can be supplemented with ambulance and
primary care data on request. PIONEER can also offer synthetic data, images and
access to a secure Trusted Research Environment for analytics and AI. PIONEER
can assist with analytics, model build, validation & refinement; A.I.; Data
partner support for ETL (extract, transform & load) process, Clinical expertise,
Patient & end-user access, Purchaser access, Regulatory requirements,
Data-driven trials, “fast screen” services.
Provenance
Origin
Purposes:
CARE
Sources:
EPR
Collection Situations:
IN-PATIENTS
Temporal
Accrual Periodicity:
QUARTERLY
Distribution Release Date:
21 December 2020
Start Date:
01 January 2015
End Date:
17 November 2020
Time Lag:
OTHER
Accessibility
Access
Access Service:
Trusted Research Environments (TRE) are built using Microsoft Azure services and
hosted in the UK to provide research teams a safe, secure and agile environment
which allows users to quickly analyse, interpret and form an enriched view of
primary care information through a range of integrated datasets. Health data
collated from multiple sources is ingested into a secure data lake which will
then allow subsets of data to be made available to research teams on approval of
a data request. Once approved a customer specific TRE is made available with a
standard set of leading analytical tools from Microsoft including Azure
Databricks, Azure Machine Learning, Azure SQL and Azure Synapse (for large-scale
data warehouses). Specific tools can be provided at an additional cost over the
standard platform data access charge and the PIONEER team will work with you to
determine your exact needs. Access to the TRE is managed using the latest
virtual desktop technology to provide a safe and secure end-user experience. By
utilising leading edge design PIONEER are able to create TREs rapidly to enable
us to service any customer requirement.
Access Request Cost:
www.pioneerdatahub.co.uk/data/data-services-costs/
Delivery Lead Time:
1-2 WEEKS
Jurisdictions:
GB-GBN
Data Controller:
University Hospitals Birmingham NHS Foundation Trust
Data Processor:
NOT APPLICABLE
Usage
Data Use Limitations:
GENERAL RESEARCH USE
Data Use Requirements:
PROJECT SPECIFIC RESTRICTIONS
Resource Creators:
- This publication uses data from PIONEER
- an ethically approved database and analytical environment (East Midlands Derby Research Ethics 20/EM/0158)
Format and Standards
Vocabulary Encoding Schemes:
- ICD10
- OPCS4
- SNOMED CT
Conforms To:
LOCAL
Languages:
en
Formats:
SQL
Observations
Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Events
26003 spells in dataset from 01.01.2015 to 17.11.2020
26003
Count
21 December 2020