client logo
Version: 1.0.0 | Published: 9 May 2025 | Updated: 391 days ago

SGLT2i use in patients with diabetes and chronic kidney disease

Dataset

Documentation

Description:
Chronic kidney disease (CKD) is a progressive condition associated with significant mortality and morbidity. It is defined by decreased renal function (demonstrated by reduced estimated glomerular filtration rate (eGFR) and/or markers of kidney damage for at least three months). More than 1.8 million people in England have diagnosed CKD, the most common causes being diabetes, hypertension and glomerulonephritis. Kidney disease affects nearly 40% of all people with diabetes during their lifetime. Well known risk factors for progression of kidney disease include poor glycaemic control hypertension and albuminuria. There is substantial evidence that tight control of these risk factors can slow down the progression of kidney disease. In addition to this recent evidence shows that use of certain reno protective drugs can confer additional benefit and improve renal outcomes in patients with diabetes. Notably, these include drugs acting on the Renin Angiotensin Aldosterone System (RAAS) as sodium glucose transported 2 receptor inhibitors and Selective mineralocorticoid receptor antagonists.

Coverage

Spatial:
West Midlands
Follow Up:
6 - 12 Months
Pathway:
ED visits, Inpatient stays and Outpatient appointments.

Provenance

Origin

Purposes:
Study
Sources:
Machine generated
Collection Situations:
  • Secondary care - Accident and Emergency
  • Secondary care - In-patients
  • Secondary care - Outpatients

Temporal

Accrual Periodicity:
Static
Distribution Release Date:
15 November 2024
Start Date:
01 October 2022
End Date:
29 September 2023
Time Lag:
More than 6 months

Accessibility

Access

Access Rights:
Information Governance and Ethics - West Midlands Secure Data Environment (https://westmidlandssde.nhs.uk/information-governance-and-ethics)
Access Service:
Data Request Process - West Midlands Secure Data Environment (https://westmidlandssde.nhs.uk/research/data-request)
Access Request Cost:
Please email wmsde@uhb.nhs.uk
Delivery Lead Time:
2-6 months
Jurisdictions:
GB
Data Controller:
University Hospitals Birmingham NHS Foundation Trust
Data Processor:
University Hospitals Birmingham NHS Foundation Trust

Usage

Data Use Limitations:
General research use
Data Use Requirements:
  • Ethics approval required
  • Project-specific restrictions
Resource Creators:
This publication uses data from the PATHWAY, an ethically approved Research Data Hub (NRES Reference 22/EE/0161)

Format and Standards

Vocabulary Encoding Schemes:
  • ICD10
  • NHS NATIONAL CODES
Conforms To:
LOCAL
Languages:
en
Formats:
SQL