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Version: 1.0.0 | Published: 18 Feb 2025 | Updated: 292 days ago

Factors Predicting Serum HLA Antibody Persistence or Decline in Kidney Transplant Patients

Dataset

Documentation

Description:
In the UK, over 8,000 patients are on the waiting list for kidney transplants. Approximately 26% of these patients are classified as highly sensitised, which significantly extends their median waiting time to around six years. The presence of HLA antibodies complicates the transplant process, as potential donors with corresponding HLA mismatches are avoided. Understanding the factors that influence the persistence or decline of HLA antibodies can aid in making informed clinical decisions and enhance the management of waiting list patients. This information is crucial for optimizing patient management and improving the chances of successful transplantation for highly sensitized patients—those with high levels of HLA antibodies who face longer waiting times and fewer compatible donor options.

Coverage

Spatial:
West Midlands

Provenance

Temporal

Accrual Periodicity:
Static
Start Date:
01 January 2015
End Date:
31 December 2021
Time Lag:
Not applicable

Accessibility

Access

Access Rights:
Information Governance and Ethics - West Midlands Secure Data Environment (https://westmidlandssde.nhs.uk/information-governance-and-ethics)
Access Service:
Data Request Process - West Midlands Secure Data Environment (https://westmidlandssde.nhs.uk/research/data-request)
Access Request Cost:
Please email wmsde@uhb.nhs.uk
Delivery Lead Time:
Variable

Usage

Resource Creators:
SDE014

Format and Standards

Vocabulary Encoding Schemes:
LOCAL
Conforms To:
LOCAL
Languages:
en
Formats:
SQL

Observations

Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Persons
1000
Count
20 February 2025