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Version: 1.0.0 | Published: 17 Feb 2025 | Updated: 376 days ago

PREVENT

Dataset

Summary

DOI Name:
10.48532/038000

Documentation

Description:
The PREVENT Research Programme has established a cohort of individuals to explore differences in the brain and cognitive function in healthy people in mid-life (aged 40-59). People are grouped into high, mid and low risk based on their family history and APOE status (a well-known risk gene for Alzheimer’s disease). Participants are assessed on biological indicators including markers in blood, saliva, urine and spinal fluid as well as direct imaging of the brain"s structure and function. Changes in all of these markers will be monitored at 2 years to work out if risks that predict these changes. One of the main aims of the study is to identify the earliest signs of changes in the brain whilst people are still in good health.

Coverage

Spatial:
United Kingdom
Typical Age Range:
40-59
Follow Up:
Continuous

Provenance

Origin

Purposes:
Study

Temporal

Accrual Periodicity:
Continuous
Start Date:
28 February 2014
Time Lag:
Not applicable

Accessibility

Access

Access Service:
The Data Portal runs its analysis environment through a virtual desktop infrastructure accessible via VMWare software. By analysing the data in the virtual desktop environment you are working on DPUK"s servers – meaning there is no physical transfer of data to researchers. The processing capacity enables you to work with large numbers of records and integrate these with the other data modalities that exist in the DPUK cohorts. This solution also offers researchers the freedom to conduct their analyses anywhere with an internet connection.
Data Controller:
West London Mental Health Trust, Imperial College London and University of Edinburgh
Data Processor:
Dementias Platform UK

Format and Standards

Vocabulary Encoding Schemes:
OTHER
Conforms To:
OTHER
Languages:
en
Formats:
CSV