Version: 1.0.0 | Published: 17 Feb 2025 | Updated: 375 days ago
Summary
DOI Name:
10.48532/034000
Documentation
Description:
The NIMROD (Neuroimaging of Inflammation in Memory and Other Disorders) study aims to understand the role of inflammation in several forms of dementia, memory loss and depression (Alzheimer"s disease, AD, dementia with Lewy bodies, DLB, progressive supranuclear palsy, PSP, frontotemporal dementia, FTD, late life depression, LLD, vascular dementia, VaD, mild cognitive impairment, MCI). The study has been set up to investigate the extent and pattern of neuroinflammation in these disorders in relation to: key clinical symptoms, including cognitive impairment, peripheral markers of neuroinflammation, including cytokine levels and state-of-the-art immunoprofiling, structural changes on MRI, including atrophy and vascular (white matter lesion) changes, the extent and pattern of brain amyloid deposition as assessed with amyloid PET imaging, the extent and pattern of tau deposition as revealed with PET. A further aim is to investigate if neuroinflammation can predict subsequent clinical course, including cognitive and functional decline.
Coverage
Spatial:
United Kingdom
Follow Up:
Continuous
Provenance
Origin
Purposes:
Study
Temporal
Accrual Periodicity:
Continuous
Start Date:
09 January 2013
Time Lag:
Not applicable
Accessibility
Access
Access Service:
The Data Portal runs its analysis environment through a virtual desktop
infrastructure accessible via VMWare software. By analysing the data in the
virtual desktop environment you are working on DPUK"s servers – meaning there is
no physical transfer of data to researchers. The processing capacity enables you
to work with large numbers of records and integrate these with the other data
modalities that exist in the DPUK cohorts. This solution also offers researchers
the freedom to conduct their analyses anywhere with an internet connection.
Data Controller:
University of Cambridge
Data Processor:
Dementias Platform UK
Format and Standards
Vocabulary Encoding Schemes:
OTHER
Conforms To:
OTHER
Languages:
en
Formats:
CSV